By Bike: By (OV-)bike is by far the easiest option. You can park your bicycle under Victor J. Koningsbergergebouw.
By Bus: If the bike is not an option, take Bus 28 and get off at Bushalte Botanische Tuinen. From there it is a 5 min walk. (fastest public transportation option)
By Tram: Take Tram 22 and get off at Halte Padualaan. From there it is a 8 min walk.
By Car: If you want to go by car (not recommended), you can park your car opposite of Minnaertgebouw (Parkeerterrein P6 – Padualaan). Be aware, the parking lot is often full and is quite expensive.